​Driving Questions

  • What is the immune landscape in cancer patients?

  • What is the immune landscape in patients prior to developing cancer?

  • What are the unique mechanisms of resistance in patients that do not respond to immunotherapy?

  • How do key immunotherapies alter the baseline immune microenvironment?

Ongoing Projects:

  1. Single cell transcriptional immune landscape of head and neck cancer (HNSCC)

  2. Control of regulatory T cell fragility in the tumor microenvironment

  3. Impact of LAG3 on T cell function in the tumor microenvironment

Selected publications:

 

The translational laboratory was established in October, 2015.  We currently have multiple manuscripts in submission, so stay tuned to see what we have been working on!