VIGNALI Laboratory

Human prostate tumor antigen-specific CD8+ regulatory T cells are inhibited by CTLA-4 or IL-35 blockade.

Olson BM, Jankowska-Gan E, Becker JT, Vignali DA, Burlingham WJ, McNeel DG.

Identity crisis: it's not just Foxp3 anymore.

Delgoffe GM, Bettini ML, Vignali DA.

Combinatorial Immunotherapy: PD-1 may not be LAG-ing behind any more.

Turnis ME, Korman AJ, Drake CG, Vignali DA.

Unexpected role for MHC II-peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo.

Do JS, Valujskikh A, Vignali DA, Fairchild RL, Min B.

IL-12 family cytokines: immunological playmakers.

Vignali DA, Kuchroo VK.

Mechanisms of T(reg) Suppression: Still a Long Way to Go.

Vignali DA.

Modulation of redox balance leaves murine diabetogenic TH1 T cells "LAG-3-ing" behind.

Delmastro MM, Styche AJ, Trucco MM, Workman CJ, Vignali DA, Piganelli JD.

T-cell receptor retrogenic mice: a rapid, flexible alternative to T-cell receptor transgenic mice.

Bettini ML, Bettini M, Vignali DA.

The battle against immunopathology: infectious tolerance mediated by regulatory T cells.

Gravano DM, Vignali DA.

Prevention of autoimmune diabetes by ectopic pancreatic β-cell expression of interleukin-35.

Bettini M, Castellaw AH, Lennon GP, Burton AR, Vignali DA.

Distinct subunit pairing criteria within the heterodimeric IL-12 cytokine family.

Jones LL, Chaturvedi V, Uyttenhove C, Van Snick J, Vignali DA.

Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency.

Bettini ML, Pan F, Bettini M, Finkelstein D, Rehg JE, Floess S, Bell BD, Ziegler SF, Huehn J, Pardoll DM, Vignali DA.

Germline TRAV5D-4 T-cell receptor sequence targets a primary insulin peptide of NOD mice.

Nakayama M, Castoe T, Sosinowski T, He X, Johnson K, Haskins K, Vignali DA, Gapin L, Pollock D, Eisenbarth GS.

Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape.

Woo SR, Turnis ME, Goldberg MV, Bankoti J, Selby M, Nirschl CJ, Bettini ML, Gravano DM, Vogel P, Liu CL, Tangsombatvisit S, Grosso JF, Netto G, Smeltzer MP, Chaux A, Utz PJ, Workman CJ, Pardoll DM, Korman AJ, Drake CG, Vignali DA.

Preferential control of induced regulatory T cell homeostasis via a Bim/Bcl-2 axis.

Wang X, Szymczak-Workman AL, Gravano DM, Workman CJ, Green DR, Vignali DA.

The composition and signaling of the IL-35 receptor are unconventional.

Collison LW, Delgoffe GM, Guy CS, Vignali KM, Chaturvedi V, Fairweather D, Satoskar AR, Garcia KC, Hunter CA, Drake CG, Murray PJ, Vignali DA.

Verification of 2A peptide cleavage.

Szymczak-Workman AL, Vignali KM, Vignali DA.

Generation of 2A-linked multicistronic cassettes by recombinant PCR.

Szymczak-Workman AL, Vignali KM, Vignali DA.

Design and construction of 2A peptide-linked multicistronic vectors.

Szymczak-Workman AL, Vignali KM, Vignali DA.