VIGNALI Laboratory

Simultaneous quantitation of 15 cytokines using a multiplexed flow cytometric assay.

Carson RT, Vignali DA.

Differential CD3 zeta phosphorylation is not required for the induction of T cell antagonism by altered peptide ligands.

Liu H, Vignali DA.

Profound enhancement of T cell activation mediated by the interaction between the TCR and the D3 domain of CD4.

​Vignali DA, Vignali KM.

Immunoregulation of Th cells by naturally processed peptide antagonists.

Carson RT, Desai DD, Vignali KM, Vignali DA.

T cell receptor recognition of MHC class II-bound peptide flanking residues

Carson RT, Vignali KM, Woodland DL, Vignali DA.

TCR-mediated adhesion of T cell hybridomas to planar bilayers containing purified MHC class II/peptide complexes and receptor shedding during detachment.

Dustin ML, Miller JM, Ranganath S, Vignali DA, Viner NJ, Nelson CA, Unanue ER.

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells.

Thierfelder WE, van Deursen JM, Yamamoto K, Tripp RA, Sarawar SR, Carson RT, Sangster MY, Vignali DA, Doherty PC, Grosveld GC, Ihle JN.

The two membrane proximal domains of CD4 interact with the T cell receptor.

Vignali DA, Carson RT, Chang B, Mittler RS, Strominger JL.

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene.

Shimoda K, van Deursen J, Sangster MY, Sarawar SR, Carson RT, Tripp RA, Chu C, Quelle FW, Nosaka T, Vignali DA, Doherty PC, Grosveld G, Paul WE, Ihle JN.

The interaction between CD4 and MHC class II molecules and its effect on T cell function.

Vignali DA.

Amino acid residues that flank core peptide epitopes and the extracellular domains of CD4 modulate differential signaling through the T cell receptor.

Vignali DA, Strominger JL.

Negative and positive selection by HLA-DR3(DRw17) molecules in transgenic mice.

Strauss G, Vignali DA, Schönrich G, Hämmerling GJ.

Interactions of CD4 with MHC class II molecules, T cell receptors and p56lck.

Vignali DA, Doyle C, Kinch MS, Shin J, Strominger JL.

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles.

Chicz RM, Urban RG, Gorga JC, Vignali DA, Lane WS, Strominger JL.

Minute quantities of a single immunodominant foreign epitope are presented as large nested sets by major histocompatibility complex class II molecules.

Vignali DA, Urban RG, Chicz RM, Strominger JL.

The dichotomy of peptide presentation by class I and class II MHC proteins.

Urban RG, Chicz RM, Vignali DA, Strominger JL.