VIGNALI Laboratory

Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease.

Ito Y, Hashimoto M, Hirota K, Ohkura N, Morikawa H, Nishikawa H, Tanaka A, Furu M, Ito H, Fujii T, Nomura T, Yamazaki S, Morita A, Vignali DA, Kappler JW, Matsuda S, Mimori T, Sakaguchi N, Sakaguchi S.

Lymphocyte Activation Gene-3 (LAG-3) negatively regulates environmentally-induced autoimmunity.

Jha V, Workman CJ, McGaha TL, Li L, Vas J, Vignali DA, Monestier M.

TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.

Bettini M, Blanchfield L, Castellaw A, Zhang Q, Nakayama M, Smeltzer MP, Zhang H, Hogquist KA, Evavold BD, Vignali DA.

Membrane association of the CD3ε signaling domain is required for optimal T cell development and function.

Bettini ML, Guy C, Dash P, Vignali KM, Hamm DE, Dobbins J, Gagnon E, Thomas PG, Wucherpfennig KW, Vignali DA.

Once a Treg, always a Treg?

Sawant DV, Vignali DA.

Regulatory T cells limit induction of protective immunity and promote immune pathology following intestinal helminth infection.

Sawant DV, Gravano DM, Vogel P, Giacomin P, Artis D, Vignali DA.

A Fox of a different color: FoxA1 programs a new regulatory T cell subset.

Delgoffe GM, Vignali DA.