It has been a busy time for the Vignali Lab. Over the past week 3 manuscripts from the lab were published in Nature Immunology, Science Immunology, and the Journal for the ImmunoTherapy of Cancer. Eager for more that are in the pipeline! Major congratulations to the first authors including Chang (Gracie) Liu PhD (NI and JITC), Lawrence Andrews PhD (SI), and Chris Chuckran (JITC).
Liu C, et al. Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity. Nature Immunology. 12 July 2020; DOI: 10.1038/s41590-020-0733-2
Chuckran CA, Liu C, et al. Neuropilin-1: a checkpoint target with unique implications for cancer immunology and immunotherapy. Journal for ImmunoTherapy of Cancer 2020;8:e000967. doi:10.1136/ jitc-2020-000967
Andrews LP, et al. Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding. Science Immunology. 17 July 2020; DOI: 10.1126/sciimmunol.abc2728.